There are many methods to determine the structure of protein, but the most precise is x-ray analysis. Protein crystallography is considered to be just a part of x-ray crystallography but it is truly important. The protein is quite complicated matter which has threefold structure, but it's become known only after the research of the secondary structure of protein. Usually, on the basis of x-ray crystallography data it is possible do define the protein quaternary texture, but it is not always available. The ability of protein structure defining depends from many different factors. The cardinal properties of protein is the protein folding. Nowadays lots of scientists endavour to complete the proper analysis of the proteins. They have already proved thoroughly that all the essential data of protein can be found in its primary texture or in protein sequence. Many very essential properties of protein as protein classification, its role are still can't be learned because of lack of knowledge about it, so we should learn more about function of protein. Even having a modern technologies and superb devices the basic problem is not solved. It is impossible to define how the texture of protein is related with its primary structure. For very short proteins, that called peptides, this problem is solved. Scientists reach success in the sphere of peptide classification. The peptide synthesis can be executed and even for various size of peptides.
Lately, the protein crystallography forum has taken place. All the information, successes, problems of crystallography of protein can be searched out in the CCP4BB. CCP4BB is a full pack of the reports of the conference that comprise some very interesting information.
Tags: crystallography, peptide, protein, protein-function, protein-problem